NEWS

Problems in the Biology of Complex Diseases

(CMM, MCB, GENE, IMB, PCOL 595H)
Friday, 9-10.50 am, Keating Bioresearch Building, Rm. 103
https://arizona.zoom.us/j/87239167386

Jan 12             Donata Vercelli (UA)                                         Overview: Complex diseases in 2024
Jan 19             Avery DeVries (UA)                                           
Complex disease epigenetics
Jan 26             Jason Karnes (UA)                                            
Genetics and pharmacogenetics of complex diseases


Feb 2               Deborah Meyers (Mayo Clinic)                     Beyond genome-wide association studies
Feb 9               Eugene Bleecker (Mayo Clinic)                    
Heterogeneity of complex lung diseases
Feb 16             Sir Stephen Holgate (U. Southampton)    
Asthma as a paradigm for complex diseases
Feb 23            Dean Billheimer (UA)                                       
The value of a P value


Mar 1              Susan Lynch (UCSF)                                         
The microbiome in complex diseases: The gut/lung axis
Mar 8             Spring Break No classes
Mar 15           Gerard Eberl (Institute Pasteur)                   
The microbiome and the gut/brain axis in immunoregulation
Mar 22          Frank Duca (UA)                                                  
The gut/brain axis in obesity and diabetes
Mar 29          Donata Vercelli (UA)                                          
How the environment protects from asthma


Apr 5             Ivan Zanoni (Harvard Medical School)        
Inflammation, a fundamental complex diseases trait
Apr 12           Isabelle Arnold (University of Zurich)         
Deconvoluting eosinophil development & function by single cell analysis
Apr 19           Casey Romanoski (UA)                                      
Addressing disease complexity through genomics
Apr 26          Yana Zavros (UA)                                                 
What is new and exciting in pancreatic cancer treatment

Presentation at the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) Annual Steering Committee Meeting

October 16-17, 2023, Rockville, MD

Vadim Pivniouk. Intranasal Administration of Amish Dust Extracts Prevents RV1B-Induced Lung Neutrophilia.

Presentations at the Collegium Internationale Allergologicum

33rd Biennial Symposium, 10-14 October 2023, Montréal, Canada

Donata Vercelli. Asthma-protective Agents in Dust from Traditional Farm Environments.

Vadim Pivniouk. Preventive but not Therapeutic Administration of a Bacterial Lysate Suppresses Experimental Allergic Asthma.

Sydney VanLinden. Transcriptional Gene Networks in the Lungs of Mice Exposed to Asthma-Protective Microbial Agents: A Comparative Analysis. 

At the Collegium Internationale Allergologicum

33rd Biennial Symposium, 10-14 October 2023, Montréal, Canada

(from the left) Avery DeVries, Donata Vercelli and Sydney VanLinden

09/2023

Sydney VanLinden was awarded a Zukowski Travel Award through the Genetics Graduate Interdisciplinary Program for the upcoming 33rd Biennial Symposium of the Collegium Internationale Allergologicum (CIA) in Montreal, Canada.

08/2023

We have a new visiting scholar, Maithreyi Prakash, participating in the Global Research Internship, a dual-degree program in Cellular and Molecular Medicine facilitated by the University of Arizona and Amrita Vishwa Vidyapeetham University in India.

08/2023

Our lab is always looking for motivated and responsible student volunteers. We will consider you if you are able to commit to at least two years in the lab.

07/2023

Sydney VanLinden was awarded an Alain L. de Weck Travel Grant for the upcoming 33rd Biennial Symposium of the Collegium Internationale Allergologicum (CIA) in Montreal, Canada.

07/2023

New publication

Vercelli D. From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease. Seminars in Immunology, 2023 Jul;68:101779. doi: 10.1016/j.smim.2023.101779. Epub 2023 May 19. PMID: 37210851.

07/2023 presentations

Donata Vercelli. Eosinophils and Microbial Signals in Asthma. Cutting Edge invite lecture, 12th Biennial Symposium, International Eosinophil Society, Hamilton, ON, Canada, July 13, 2023.

06/2023

Sydney VanLinden has been selected as a NIEHS Predoctoral Trainee in Environmental Toxicology of Human Disease through the Pharmacology and Toxicology Department.

06/2023

New publication

Marques dos Santos M., V. Pivniouk, B. Rankl, A. Walker, G. Pagani, N. Hertkorn, P. Schmitt-Kopplin, C. Müller, F. Bracher, J. Merl-Pham, S.M. Hauck, M. Schloter, A.N. Michael, D. Anderson, L. Honeker, J. Gozdz, O. Pivniouk, M. Holbreich, F.D. Martinez, S.A. Snyder, E. von Mutius and D. Vercelli. Asthma-protective agents in dust fron traditional farm environments. J. Allergy Clin. Immunol.(2023) Online ahead of print. PMID: 37271318

05/2023 presentations

Donata VercelliMicrobial Agents and Asthma Protection. Environmental Health and Lung Research School Distinguished Speakers Series, Helmholtz Munich, Munich, Germany, May 11, 2023 (online)

Pivniouk Vadim, O. Pivniouk, J.L. Uhrlaub, A. Molzahn, H. Kimura, M. Kraft, J. Nikolich-Zugich and D. Vercelli. IL-13 protects epithelial cells from SARS-CoV-2 infection by inhibiting early ACE2-mediated events. Annual Meeting, American Association of Immunologists, Washington, DC, May 11-15, 2023

DeVries Avery, P. Ezeh, D. Anderson, M. Holbreich, V. Pivniouk, C. Ober, and D. Vercelli. Consensus network analysis identifies core transcriptional pathways that prevent disruption of the human airway epithelial barrier. International Conference, American Thoracic Society, Washington, DC, May 19-24, 2023

Donata Vercelli. What Are Key Immune Mechanisms for Asthma Onset in Humans? Expert Panel, OM Pharma, Geneva, Switzerland, May 31, 2023

03-04/2023 presentations

Donata Vercelli. Immunomodulations: A new tool against SARS-CoV-2? Asthma & Infection Immunity Academy, Qingdao, China, March 25, 2023 (online)

Donata Vercelli. What Are Key Immune Mechanisms for Asthma Onset in Humans? European Respiratory Society Research Seminar, Are We Ready to Translate Epidemiological and Mechanistic Studies into Reality? Berlin, Germany, April 17, 2023

02/2023

Donata Vercelli has been elected Fellow of the American Association for the Advancement of Science (AAAS), a distinct honor in the scientific community.

https://healthsciences.arizona.edu/connect/honors/0323/dr-donata-vercelli-named-2022-aaas-fellow

01/2023

New publications

Vercelli D. and S.V. Lynch. Interactions between host epigenetics and microbiota: Who does what to whom, when and why? Perspective, J. Allergy Clin. Immunol. PMID: 36720286

Pivniouk V. and Vercelli D. The OM-85 bacterial lysate: A new tool against SARS-CoV-2? Multidiscip. Respir. Med. 18:906 PMID: 36798954

09/2022

HRH King Charles III hosted a global symposium of allergy scientists — Natasha Allergy Research Foundation – narf.org.uk

Professor Sir Stephen Holgate, Professor of Immunopharmacology at the University of Southampton, a World Allergy Organisation Centre of Excellence, who has successfully campaigned for air pollution to be recognised as an asthma-related cause of death. Speakers included: Tari Haahtela, Professor of the University of Helsinki in Finland, who introduced the theory in 2011 that global loss of …

www.narf.org.uk

07/2022

Avery’s paper was accepted for publication!

DeVries, A., K. McCauley, D. Fadrosh, K. Lynch, K.E. Fujimura, D.A. Stern, S.V. Lynch, and D. Vercelli. Maternal prenatal immunity, neonatal trained immunity, and early airway microbiota shape childhood asthma development. Allergy 2022 Jul 16. doi: 10.1111/all.15442. Online ahead of print.
PMID: 35841380

06/2022

We have a visiting scholar, Varna Sree Kumar, participating in the Global Research Internship, a dual-degree program in Cellular and Molecular Medicine facilitated by the University of Arizona and Amrita Vishwa Vidyapeetham University in India.